SS-31

SS-31 in Laboratory Research

SS-31 (elamipretide) is a four-residue peptide with an alternating aromatic-cationic structure that causes it to concentrate at the inner mitochondrial membrane, where it binds the phospholipid cardiolipin selectively. That targeted interaction is what makes it a distinctive tool compound in mitochondrial research.

Research groups use SS-31 in controlled laboratory systems to study how stabilising cardiolipin influences the organisation and function of the mitochondrial membrane.

Research Applications & Study Focus

Most work involving SS-31 focuses on electron-transport-chain efficiency, reactive-oxygen-species generation, and the structural stability of cristae. It appears in preclinical models of mitochondrial dysfunction, ischemia-reperfusion injury, age-related muscle loss, and neurodegeneration.

It is offered in 10 mg and 50 mg vials, and its reproducible lot specification supports consistent assay conditions across repeated mitochondrial experiments.

Purity, Handling & Verification

Each batch is supplied as a sealed, lyophilized vial and is independently analysed by a third-party laboratory using HPLC and mass spectrometry; the full certificate of analysis is published against its lot number, so results can be verified before use. Store the lyophilized material cool, dry and out of direct light, and reconstitute with bacteriostatic water under standard aseptic laboratory practice.

This material is offered strictly for in vitro laboratory research use only. It is not for human or veterinary consumption, and not for diagnostic or therapeutic use.